## Background: The presence of regional metastasis in patients with head and neck squamous cell carcinoma (hnscc) is a common and adverse event associated with poor prognosis and high mortality. although significant improvements in standard therapies have increased the efficacy of local tumor manag
Molecular pathogenesis of head and neck squamous cell carcinoma
β Scribed by David Hardisson
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 166 KB
- Volume
- 260
- Category
- Article
- ISSN
- 0302-9530
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## Background: Squamous cell carcinoma (scc) of the head and neck region is rare in young patients and even less frequent in children 15 years or younger children. the patients reported in the literature are isolated cases and their management is always difficult because there is no large experienc
## Abstract ## Background Germline mutations at the __INK4a/p16__ locus are implicated in several human cancer syndromes, including familial atypical multiple mole melanoma (FAMMM) syndrome, FAMMMβpancreatic cancer (FAMMMβPC) syndrome, and in familial head and neck cancer syndrome. ## Methods We