The molecular mechanism of gastric tumourigenesis has not yet been clarified, although investigators have postulated that differentiated adenocarcinoma may arise from pre-existing adenoma, similarly to the colorectal adenoma-carcinoma sequence. An allelotype analysis has been performed to identify c
โฆ LIBER โฆ
Molecular pathogenesis of adenoma and differentiated adenocarcinoma of the stomach
โ Scribed by Gen Tamura
- Book ID
- 115175170
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 721 KB
- Volume
- 46
- Category
- Article
- ISSN
- 1320-5463
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In a recent allelotypic analysis of differentiated adenocarcinoma of the stomach, loss of heterozygosity (LOH) was found frequently on chromosomes 2q, 4p, 5q, 6p, 7q, 11q, 14q, 17p, 18q, and 21q. To clarify the sequence of these chromosomal losses during gastric carcinogenesis, microsatellite analys