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Molecular monitoring ofBAALCexpression in patients with CD34-positive acute leukemia

✍ Scribed by Yuho Najima; Kazuteru Ohashi; Machiko Kawamura; Yuji Onozuka; Toshikazu Yamaguchi; Hideki Akiyama; Hisashi Sakamaki

Book ID
107619002
Publisher
Carden Jennings Publishing
Year
2010
Tongue
English
Weight
495 KB
Volume
91
Category
Article
ISSN
0925-5710

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## Abstract ## BACKGROUND Alemtuzumab is a humanized monoclonal antibody directed against the cell surface antigen CD52 and has demonstrated activity in chronic lymphocytic leukemia and other CD52‐positive lymphoproliferative disorders. Because CD52 also is expressed on acute leukemic blasts, the