## Abstract The wellβestablished molecular pathogenesis of chronic myelogenous leukemia (CML) and its consequences for laboratory testing and clinical management illustrate a classic paradigm for the importance of molecular diagnostics in targeted drug therapy. The success of the tyrosine kinase in
Molecular monitoring in patients with chronic myelogenous leukemia
β Scribed by Giuseppe Saglio; Stefano Ulisciani; Milena Fava; Enrico Gottardi; Daniela Cilloni
- Book ID
- 107540204
- Publisher
- Current Science Inc.
- Year
- 2008
- Tongue
- English
- Weight
- 174 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1558-8211
No coin nor oath required. For personal study only.
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## Abstract Rapid developments have occurred both in laboratory medicine and in therapeutic interventions for the management of patients with chronic myelogenous leukemia (CML). With a wide array of laboratory tests available, selecting the appropriate test for a specific diagnostic or therapeutic
## Background: Allogeneic stem cell transplantation (sct) and interferon (ifn)-alpha therapy have significantly improved the prognosis of patients with philadelphia (ph) chromosome positive chronic myelogenous leukemia (cml). both therapies may be suitable for younger patients. the authors reviewed