𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular modeling of the von Willebrand factor A2 Domain and the effects of associated type 2A von Willebrand disease mutations

✍ Scribed by Jeffrey J. Sutherland; Lee A. O’Brien; David Lillicrap; Donald F. Weaver

Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
523 KB
Volume
10
Category
Article
ISSN
1610-2940

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Diagnosis of von Willebrand disease type
Diagnosis of von Willebrand disease type 2N: A simplified method for measurement of factor VIII binding to von Willebrand factor
✍ Miller, Connie H.; Kelley, Leslie; Green, David 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB 👁 2 views

## Diagnosis of von Willebrand disease Type 2N (vWD 2N ), which mimics hemophilia A and its carrier state, is important for accurate genetic counseling and appropriate therapy. To make testing for the disorder more clinically applicable, we developed a simplified method for measurement of factor V

Identification of a new candidate mutati
Identification of a new candidate mutation, G1629R, in a family with type 2A von Willebrand disease
✍ Casa�a, Pilar; Mart�nez, Francisco; Haya, Saturnino; Aznar, Jos� A. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 1 views

Type 2A is a qualitative variant of von Willebrand disease (vWD) characterized by a reduced platelet-dependent function, associated with an absence of large multimers. A G5135A transition, resulting in a glycine to arginine substitution at the codon 1629 of the von Willebrand factor, was identified