Review of previous edition: βI am often asked by physicists, mathematicians and engineers to recommend a book that would be useful to get them started in computational molecular biology. I am also often approached by my colleagues in computational biology to recommend a solid textbook for a graduate course in the area. Tamar Schlick has written the book that I will be recommending to both groups. Tamar has done an amazing job in writing a book that is both suitably accessible for beginners, and suitably rigorous for experts.β J. J. Collins, Boston University, USA. βMolecular modeling β¦ is now an important branch of modern biochemistry. β¦ Schlick has brought her unique interdisciplinary expertise to the subject. β¦ One of the most distinguished characteristics of the book is that it makes the reading really fun β¦ and the material accessible. β¦ a crystal clear logical presentation β¦ . Schlick has added a unique title to the collection of mathematical biology textbooks β¦ . a valuable introduction to the field of computational molecular modeling. It is a unique textbook β¦ .β Hong Qian, SIAM Review, 2005.