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Molecular Mimicry and Antigen-Specific T Cell Responses in Multiple Sclerosis and Chronic CNS Lyme Disease

✍ Scribed by Roland Martin; Bruno Gran; Yingdong Zhao; Silva Markovic-Plese; Bibiana Bielekova; Adriana Marques; Myong-Hee Sung; Bernhard Hemmer; Richard Simon; Henry F McFarland; Clemencia Pinilla


Book ID
115621835
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
118 KB
Volume
16
Category
Article
ISSN
0896-8411

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✍ T. Vu; L.W. Myers; G.W. Ellison; F. Mendoza; J.M. Bronstein πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 119 KB

## Abstract Oligodendrocyte‐specific protein (OSP) is concentrated in CNS myelin and is a potential autoantigen in the development of multiple sclerosis (MS). We performed proliferation assays with lymphocytes from MS patients and normal controls. OSP peptide‐induced proliferation was common in rel