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[Molecular Medicine and Medicinal Chemistry] Molecular Exploitation of Apoptosis Pathways in Prostate Cancer Volume 5 || Epithelial–Mesenchymal Transition (EMT) in Prostate Cancer Metastasis

✍ Scribed by Kyprianou, Natasha

Book ID
120252559
Publisher
IMPERIAL COLLEGE PRESS
Year
2012
Tongue
English
Weight
135 KB
Edition
2
Category
Article
ISBN
1848164505

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✦ Synopsis

This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of resistance by androgen-independent tumors are introduced, in terms of the contribution of anoikis and cross-talk of androgens with key growth factor signaling pathways. This volume also provides insightful discussion on the exploitation of the apoptotic and angiogenic synergism towards complete eradication of prostate tumors. Last but not least, it includes reflections on the drug development challenge based on the analysis of data from existing clinical trials.

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This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of resistance by androgen-independent tumors are introduced, in terms of the contribution of anoikis and cross-talk of androgens wi