✦ LIBER ✦

Molecular mechanisms underlying functional T-cell unresponsiveness

✍ Scribed by Daniel L. Mueller; Marc K. Jenkins

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 812 KB
Volume: 7
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(95)80113-8

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✦ Synopsis

Evidence from tissue culture experiments and in vivo studies indicates that certain forms of antigen presentation render T cells unresponsive to subsequent antigenic stimulation. Great progress has been made recently in understanding the induction, maintenance, and in vivo relevance of this unresponsive state, called clonal anergy.

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