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Molecular Mechanisms of Transition-State Stabilization in Catalytic Antibodies

✍ Scribed by Takeshi Tsumuraya; Ikuo Fujii

Book ID
111699722
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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On the Generation of Catalytic Antibodie
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✍ Montserrat Barbany; Hugo GutiΓ©rrez-de-TerΓ‘n; Ferran Sanz; Jordi VillΓ -Freixa; Ar πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 180 KB

## Abstract __The effective design of catalytic antibodies represents a major conceptual and practical challenge. It is implicitly assumed that a proper transition state analogue (TSA) can elicit a catalytic antibody (CA) that will catalyze the given reaction in a similar way to an enzyme that woul