The AML1/EVI-1 chimeric gene is generated by the t(3;21)(q26;q22) translocation and plays a pivotal role in progression of hematopoietic stem cell malignancies such as chronic myelocytic leukemia and myelodysplastic syndrome. In AML1/EVI-1, an N-terminal half of AML1 including a runt homology domain
โฆ LIBER โฆ
Molecular mechanisms of leukemogenesis by AML1/EVI-1
โ Scribed by Mitani, Kinuko
- Book ID
- 110068846
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 247 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0950-9232
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