Molecular mechanisms of dominant expression in porphyria
โ Scribed by M. N. Badminton; G. H. Elder
- Book ID
- 106373991
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 154 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0141-8955
No coin nor oath required. For personal study only.
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Lewis antigens comprise type 1 (Lewis a, Lewis b) and type 2 (Lewis X, Lewis Y) carbohydrates. Lewis X and Lewis Y are regarded as tumor-associated markers, and some of these antigens and their derivatives interact with selectins, mediating cell-to-cell adhesion. In addition, Lewis b on the gastric
In four of the five autosomal dominant porphyrias four different partial enzymatic defects of the porphyrin biosynthetic pathway have been discovered in the last few years. With the exception of protoporphyria, the residual enzymatic activity in carriers of these defects is approximately equal to 50