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Molecular mechanisms of B-lymphocyte transformation by Epstein–Barr virus

✍ Scribed by Gail A. Bishop; Lisa K. Busch


Book ID
108489006
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
67 KB
Volume
4
Category
Article
ISSN
1286-4579

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By rosetting with SRBC coupled to rabbit-anti-human IgM, the surface IgM-negative cells of human fetal bone marrow were enriched, and subsequently infected and transformed by Epstein-Barr virus (EBV). Single clones of the transformed cells were obtained. Ninety percent of the resulting cell clones w