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Molecular mechanisms involved in endothelial cell aging: role of telomerase reverse transcriptase

✍ Scribed by S. Jakob; J. Haendeler

Book ID: 106063405
Publisher: Springer
Year: 2007
Tongue: English
Weight: 169 KB
Volume: 40
Category: Article
ISSN: 0948-6704
DOI: 10.1007/s00391-007-0482-y

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## Abstract We previously reported that 3‐methylcholanthrene (3MC), an aryl‐hydrocarbon receptor (AhR) agonist, inhibits the proliferation of human umbilical vascular endothelial cells (HUVECs; Juan et al., 2006, Eur J Pharmacol 530: 1–8). Herein, pretreatment of HUVECs with p21 or p27 small interf