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Molecular mechanisms associated with long-term consolidation of the NMDA signals

✍ Scribed by Jan Plátenı́k; Nobuyuki Kuramoto; Yukio Yoneda

Book ID
117172386
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
612 KB
Volume
67
Category
Article
ISSN
0024-3205

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Recent work has shown that kynurenic acid and several quinoxaline derivatives act as non-competitive NMDA receptor antagonists by binding to the glycine site associated with this receptor. In this study, we have tested the effect of the most potent and selective of these compounds, 7-chlorokynurenic