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Molecular mechanisms and imaging of lymphatic metastasis

✍ Scribed by Proulx, Steven T.; Detmar, Michael


Book ID
120037769
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
520 KB
Volume
319
Category
Article
ISSN
0014-4827

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The molecular changes associated with the transition of melanoma cells from radial growth phase to vertical growth phase (metastatic phenotype) are not very well defined. Expression of the tyrosine-kinase receptor c-KIT progressively decreases during local tumor growth and invasion of human melanoma