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Molecular Mechanism of Urea-Induced Protein Denaturation

โœ Scribed by Lee, Soyoung; Shek, Yuen Lai; Chalikian, Tigran V.


Book ID
119206243
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
37 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract To understand the mechanism of ionic detergentโ€induced protein denaturation, this study examines the action of sodium dodecyl sulfate on ferrocytochrome __c__ conformation under neutral and strongly alkaline conditions. Equilibrium and stoppedโ€flow kinetic results consistently suggest t