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Molecular mechanism of the neurotrophic effect of GDNF on DA neurons: role of protein kinase CK2

✍ Scribed by Chih C. Chao; Cheng H. Chiang; Yun L. Ma; Eminy H.Y. Lee

Book ID
116780634
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
585 KB
Volume
27
Category
Article
ISSN
0197-4580

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## Abstract Protein kinase CK2 (casein kinase II) is normally a heterotetramer composed of catalytic (Ξ±, Ξ±β€²) and regulatory subunits (Ξ²). CK2 is able to phosphorylate a large number of protein substrates but the physiological mechanisms of its regulation are still unresolved. Lysine‐rich peptides s