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Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3

โœ Scribed by Masahiro Nagase; Tetsuya Shiota; Akiko Tsushima; Mohammad Murshedul Alam; Satoshi Fukuoka; Takumi Yoshizawa; Nobuo Sakato

Book ID
108408301
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
190 KB
Volume
84
Category
Article
ISSN
0165-2478

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## Abstract Thymoquinone (TQ), the major biologically active component isolated from a traditional medicinal herb, __Nigella sativa__ Linn, is a potential chemopreventive and chemotherapeutic compound. Despite the promising antineoplastic activities of TQ, the molecular mechanism of its pharmacolog