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Molecular Mechanism of p73-Mediated Regulation of Hepatitis B Virus Core Promoter/Enhancer II: Implications for Hepatocarcinogenesis

✍ Scribed by Sven Buhlmann; Tomas Racek; Alexandra Schwarz; Stephan Schaefer; Brigitte M. Pützer


Book ID
116663745
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
851 KB
Volume
378
Category
Article
ISSN
0022-2836

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The incidence of hepatocellular carcinoma (HCC) is particularly high in regions of Asia and sub-Saharan Africa where rates of infection with human hepatitis-B virus (HBV) and aflatoxin-BI contamination of food are high. In HCC tumors occurring in inhabitants of these regions, a G-to-T mutation frequ