Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms
โ Scribed by Giorgio Sesti; Massimo Federici; Davide Lauro; Paolo Sbraccia; Renato Lauro
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 171 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1520-7552
- DOI
- 10.1002/dmrr.225
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## Abstract The positive regulatory role of PSM/SH2โB downstream of various mitogenic receptor tyrosine kinases or gene disruption experiments in mice support a role of PSM in the regulation of insulin action. Here, four alternative PSM splice variants and individual functional domains were compare