Molecular Mechanism of Inhibition of the Human Protein Complex Hsp90–Cdc37, a Kinome Chaperone–Cochaperone, by Triterpene Celastrol

✍ Scribed by Sridhar Sreeramulu; Santosh Lakshmi Gande; Michael Göbel; Harald Schwalbe

• Book ID: 101570191
• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 399 KB
• Volume: 48
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200900929

✦ Synopsis

further understand the molecular for inhibiting this key Cdc37-Hsp90 complex in cancer cells.