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Molecular markers and targets for colorectal cancer prevention

✍ Scribed by Naveena B JANAKIRAM; Chinthalapally V RAO


Book ID
111357139
Publisher
Nature Publishing Group
Year
2008
Tongue
Chinese
Weight
595 KB
Volume
29
Category
Article
ISSN
1671-4083

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## Abstract Cyclooxygenase‐2 (COX‐2) is an inducible enzyme that regulates prostaglandin synthesis and is overexpressed at sites of inflammation and in several epithelial cancers. A causal link for COX‐2 in epithelial tumorigenesis was shown in genetically manipulated animal models of colon and bre