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Molecular lesions in childhood and adult acute megakaryoblastic leukaemia

✍ Scribed by Asahito Hama; Hideki Muramatsu; Hideki Makishima; Yuka Sugimoto; Hadrian Szpurka; Monika Jasek; Christine O’Keefe; Yoshiyuki Takahashi; Hirotoshi Sakaguchi; Sayoko Doisaki; Akira Shimada; Nobuhiro Watanabe; Koji Kato; Hitoshi Kiyoi; Tomoki Naoe; Seiji Kojima; Jaroslaw P. Maciejewski


Book ID
108677505
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
363 KB
Volume
156
Category
Article
ISSN
0007-1048

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Routine morphologic and cytochemical study of the leukemic cells of a 13-month-old child did not permit definitive determination of either a lymphoid or a myeloid cell origin. However, ultrastructural cytochemical analysis revealed platelet peroxidase (PPO) reactivity. The malignant cells expressed