Human immunodeficiency virus type 1 tat
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David S. K. Magnuson; Bodo E. Knudsen; Jonathan D. Geiger; Robert M. Brownstone;
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Article
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1995
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John Wiley and Sons
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English
⚖ 707 KB
## Abstract The human immunodeficiency virus type 1 (HIV‐1) protein Tat is known to be released from HIV‐1‐infected cells. We show that micromolar concentrations of Tat depolarized young rat and adult human neurons. In addition, Tat, at similar concentrations, was toxic to human fetal neurons in cu