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Molecular interactions of the type 1 human immunodeficiency virus transregulatory protein Tat with N-methyl-d-aspartate receptor subunits

✍ Scribed by T. Chandra; W. Maier; H.-G. König; K. Hirzel; D. Kögel; T. Schüler; A. Chandra; I. Demirhan; B. Laube


Book ID
116786989
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
283 KB
Volume
134
Category
Article
ISSN
0306-4522

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Human immunodeficiency virus type 1 tat
✍ David S. K. Magnuson; Bodo E. Knudsen; Jonathan D. Geiger; Robert M. Brownstone; 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 707 KB

## Abstract The human immunodeficiency virus type 1 (HIV‐1) protein Tat is known to be released from HIV‐1‐infected cells. We show that micromolar concentrations of Tat depolarized young rat and adult human neurons. In addition, Tat, at similar concentrations, was toxic to human fetal neurons in cu