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Molecular Imaging of Tumor-Associated Angiogenesis Using a Novel Magnetic Resonance Imaging Contrast Agent Targeting αvβ3Integrin

✍ Scribed by Debergh, Isabelle; Damme, Nancy; Naeyer, Dieter; Smeets, Peter; Demetter, Pieter; Robert, Philippe; Carme, Sabin; Pattyn, Piet; Ceelen, Wim

Book ID
121586226
Publisher
Springer
Year
2013
Tongue
English
Weight
578 KB
Volume
21
Category
Article
ISSN
1068-9265

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## Abstract ## Purpose: To investigate the targeting activity of the peptide (named P1c) derived from connective tissue growth factor (CTGF) to αvβ3‐rich tumor cells. ## Materials and Methods: P1c was synthesized and conjugated with ultrasuperparamagnetic iron oxide particles (USPIOs) coated wit