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Molecular imaging of alkylguanine-DNA alkyltransferase: further evaluation of radioiodinated derivatives of O6-benzylguanine

✍ Scribed by Sriram Shankar; Michael R. Zalutsky; Henry Friedman; Ganesan Vaidyanathan

Book ID
116798968
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
272 KB
Volume
33
Category
Article
ISSN
0969-8051

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## Abstract Novel radiolabeled O^6^‐benzylguanine derivatives, 2‐amino‐6‐O‐[^11^C]‐[(methoxymethyl)benzyloxy]‐9‐benzyl purines ([^11^C]__p__‐O^6^‐AMBP, **1a**; [^11^C]__m__‐O^6^‐AMBP, **1b**; [^11^C]__o__‐O^6^‐AMBP, **1c**), have been synthesized for evaluation as new potential positron emission to