Molecular identification of a danger signal that alerts the immune system to dying cells
โ Scribed by Shi, Yan; Evans, James E.; Rock, Kenneth L.
- Book ID
- 109891411
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 842 KB
- Volume
- 425
- Category
- Article
- ISSN
- 0028-0836
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The immune system was recognized in ancient times and rediscovered by Jenner and Pasteur based on its ability to confer protection against repeat exposure to a pathogen. Through subsequent studies by von Behring and others, it rapidly became apparent that the immune system has the potential to respo
P50/KIR2DS molecules represent the activating form of the HLA-C-specific inhibitory NK receptors. They are characterized, in the transmembrane portion, by a charged amino acid that is involved in coupling with signal-transducing adaptor polypeptides. In this study we identified a novel p50.2/KIR2DS2