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Molecular Heterogeneity of Glucose-6-Phosphate Dehydrogenase Deficiency in Malays in Malaysia

✍ Scribed by Narazah Mohd Yusoff; Taku Shirakawa; Kaoru Nishiyama; Selamah Ghazali; Choo Keng Ee; Ayako Orita; Wan Zaidah Abdullah; Mohd Nizam Isa; Hans Van Rostenberghe; Masafumi Matsuo

Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
150 KB
Volume
76
Category
Article
ISSN
0925-5710

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We performed DNA analysis using cord blood samples on 86 male Malay neonates diagnosed as G6PD deficiency in the National University of Malaysia Hospital by a combination of rapid PCR-based techniques, single-stranded conformation polymorphism analysis (SSCP) and DNA sequencing. We found 37.2% were