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Molecular genetics of Usher syndrome

✍ Scribed by J. D. Eudy; J. Sumegi


Publisher
Springer
Year
1999
Tongue
English
Weight
841 KB
Volume
56
Category
Article
ISSN
1420-682X

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Wiedemann-Beckwith syndrome (WBS) is a heterogeneous overgrowth syndrome associated with malformations and an elevated risk of developing embryonal tumors. WBS is a multigenic disorder caused by dysregulation of imprinted growth regulatory genes within the 11p15 region. Elucidation of the genetic ca