Clonality of T-and 6-cell lymphoproliferative disorders can be determined by gene rearrangement studies when morphology and surface immunostaining are nondiagnostic. TcR and Ig gene rearrangements have been demonstrated in many different hematologic disorders and TcR gene rearrangement has been part
Molecular genetics of mitochondrial disorders
โ Scribed by Lee-Jun C. Wong
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Tongue
- English
- Weight
- 797 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1940-5510
- DOI
- 10.1002/ddrr.104
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Despite the strong genetic basis of autism spectrum disorders (ASD), research efforts in the last decade have not been successful in the identification of confirmed susceptibility genes. We review the present status of genetic linkage, candidate gene, and association studies, pointing o
Mutations in the POLG gene have emerged as one of the most common causes of inherited mitochondrial disease in children and adults. They are responsible for a heterogeneous group of at least 6 major phenotypes of neurodegenerative disease that include: 1) childhood Myocerebrohepatopathy Spectrum dis