Molecular genetics and cytogenetics of wilms' tumor
β Scribed by Louise C. Strong; Vicki Huff; Duane A. Compton; Michael M. Weil; Grady F. Saunders
- Book ID
- 119104268
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 81 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0165-4608
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π SIMILAR VOLUMES
Wilms tumor (WT), a sporadic and familial childhood kidney tumor, is genetically heterogeneous. One WT gene, WT1 at 11p13, has been cloned, but only a minority of WTs carry detectable mutations at that locus. WT1 can also be excluded as the predisposition gene in most WT families, implying the exist
## Abstract A complete family history was obtained for 501 patients with Wilms' tumor, treated in departments of pediatric oncology in whole France. The information was collected by selfβquestionnaire and/or by interview of parents. The proportion of bilateral cases is 4.6% and there are 12 patient