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Molecular genetic cause of X-linked retinitis pigmentosa in a Czech family

✍ Scribed by Petra Liskova; Tracy Colclough; Niki Hart-Holden; Christina F. Chakarova; Anna O’Grady; Lucie Kondrova; Pavlina Skalicka; Pavel Diblik; Alison J. Hardcastle


Book ID
118075946
Publisher
Wiley (Blackwell Publishing)
Year
2011
Tongue
English
Weight
214 KB
Volume
89
Category
Article
ISSN
1755-375X

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A family with RP3 type of X-linked retin
✍ Dieuwke B. Dorp; Alan F. Wright; Andrew D. Carothers; Elizabeth M. Bleeker-Wagem 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 446 KB

The results of linkage analysis in a family with X-linked retinitis pigmentosa (XLRP) are presented. Probe M27B (DXS255), localised to Xpll.22, was only loosely linked to XLRP, whereas pHOC3 (OTC), in the more distal Xp21.1 region, was tightly linked. In this family, the conditional probability of a