𝔖 Bobbio Scriptorium
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Molecular genetic aspects of prostate transition zone lesions

✍ Scribed by Jasminka Pavelić; Z̆arko Zeljko; Maja Herak Bosnar


Book ID
117265347
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
114 KB
Volume
62
Category
Article
ISSN
0090-4295

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Loss of heterozygosity (LOH) and microsatellite instability (MSI) have been shown to be mechanisms for tumor-suppressor gene inactivation in human oncogenesis. In our study, we examined LOH and MSI using 16 polymorphic markers of DNA for chromosomes 1, 3, 7, 8, 10 and 11. Microdissected tumor sample