Molecular genetic approach to the characterization of the “Down syndrome region” of chromosome 21
✍ Scribed by MCCORMICK, M
- Book ID
- 122920913
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 800 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0888-7543
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The largest class of de novo chromosomal rearrangements in Down syndrome are rea(21q21q). Classically, these rearrangements have been termed Robertsonian translocations, implying an attachment of two different chromosome 21 homologues. Additionally, a Robertsonian translocation between two chromosom
## Abstract Down syndrome is usually caused by complete trisomy 21. Rarely, it is due to partial trisomy of the segment 21q22. We report on a 33‐month‐old girl with tetrasomy 21 pter → q22.1 resulting from an extra chromosome idic(21)(q22.1). She has craniofacial traits typical of Down syndrome, in