In this study, we analyzed 10 human squamous cell carcinomas (SCCs) for alterations in the p53 tumor suppressor gene in exons 4 through 9 by single-strand conformation polymorphism (SSCP) analysis. We found that 2 of 10 SCCs displayed unusual SSCP alleles at exon 7 of the p53 gene. Subsequent clonin
β¦ LIBER β¦
Molecular genetic analysis of the BRCA2 tumor suppressor gene region in cutaneous squamous cell carcinomas
β Scribed by Sarah E. Gray; Elaine Kay; Mary Leader; Mohamed Mabruk
- Book ID
- 111242199
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 578 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0303-6987
No coin nor oath required. For personal study only.
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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing Λ90% of all oral carcinomas and accounting for 3β5% of all malignancies. The __WWOX__ gene (WWβdomain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q
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