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Molecular genetic alterations in endometrioid carcinomas of the ovary: Similar frequency of beta-catenin abnormalities but lower rate of microsatellite instability and PTEN alterations than in uterine endometrioid carcinomas

✍ Scribed by Lluis Catasús; Elena Bussaglia; Ingrid Rodrı́guez; Alberto Gallardo; Cristina Pons; Julie A. Irving; Jaime Prat

Book ID: 116533811
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 443 KB
Volume: 35
Category: Article
ISSN: 1532-8392
DOI: 10.1016/j.humpath.2004.07.019

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## BACKGROUND. The two most common types of uterine endometrial carcinoma, endometrioid (UEC) and serous (USC), differ in their histopathologic appearance and biologic behavior. Recent studies suggest that these differences may be associated with distinct molecular genetic alterations. ## METHODS.