Molecular gears with two-toothed and three-toothed wheels

Molecular analysis in Japanese patients

Molecular analysis in Japanese patients with Charcot-Marie-Tooth disease: DGGE analysis for PMP22, MPZ, and Cx32/GJB1 mutations

✍ Chikahiko Numakura; Changqing Lin; Tohru Ikegami; Per Guldberg; Kiyoshi Hayasaka 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 169 KB

Charcot-Marie-Tooth disease (CMT) is a heterogeneous disorder and is traditionally classified into two major types, CMT type 1 (CMT1) and CMT type 2 (CMT2). Most CMT1 patients are associated with the duplication of 17p11.2-p12 (CMT1A duplication) and small numbers of patients have mutations of the p