Wiedemann-Beckwith syndrome (WBS) is a heterogeneous overgrowth syndrome associated with malformations and an elevated risk of developing embryonal tumors. WBS is a multigenic disorder caused by dysregulation of imprinted growth regulatory genes within the 11p15 region. Elucidation of the genetic ca
Molecular Findings in Beckwith-Wiedemann Syndrome
✍ Scribed by CHOUFANI, SANAA; SHUMAN, CHERYL; WEKSBERG, ROSANNA
- Book ID
- 121082224
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 737 KB
- Volume
- 163
- Category
- Article
- ISSN
- 1552-4868
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📜 SIMILAR VOLUMES
The Wiedemann-Beckwith syndrome (WBS) comprises an accumulation of multiple congenital anomalies. Exomphalos, macroglossia and gigantism are considered the most common manifestations, hence the alternative designation EMG-syndrome. The syndrome carries with it an increased risk of developing specifi
## Abstract Beckwith–Wiedemann syndrome (BWS) is a clinically heterogeneous overgrowth syndrome associated with an increased risk for embryonal tumor development. BWS provides an ideal model system to study epigenetic mechanisms. This condition is caused by a variety of genetic or epigenetic altera