Molecular evolution of the carbonic anhydrase genes: Calculation of divergence time for mouse carbonic anhydrase I and II
β Scribed by Peter J. Fraser; Peter J. Curtis
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 488 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-2844
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A practical laboratory experiment is described that illustrates the application of fluorescence resonance energy transfer to the study of proteinβligand binding. The affinities of wildβtype and mutant human carbonic anhydrase II for dansylamide were determined by monitoring the increase
In this paper, the carbonic anhydrase II (CA II) enzyme active site is modeled using ab initio calculations and molecular dynamics simulations to examine a number of important issues for the enzyme function. It is found that the Zn 2Ψ ion is dominantly tetrahedrally coordinated, which agrees with X-