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Molecular evolution of immunoglobulin and fibronectin domains in titin and related muscle proteins

โœ Scribed by Paraic A. Kenny; Eibhlis M. Liston; Desmond G. Higgins


Book ID
117523605
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
565 KB
Volume
232
Category
Article
ISSN
0378-1119

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The evolution of titin and related giant
โœ Desmond G. Higgins; Siegfried Labeit; Mathias Gautel; Toby J. Gibson ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 914 KB

Titin and twitchin are giant proteins expressed in muscle. They are mainly composed of domains belonging to the fibronectin class III and immunoglobulin c2 families, repeated many times. In addition, both proteins have a protein kinase domain near the C-terminus. This paper explores the evolution of