The evolution of titin and related giant
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Desmond G. Higgins; Siegfried Labeit; Mathias Gautel; Toby J. Gibson
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Article
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1994
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Springer
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English
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Titin and twitchin are giant proteins expressed in muscle. They are mainly composed of domains belonging to the fibronectin class III and immunoglobulin c2 families, repeated many times. In addition, both proteins have a protein kinase domain near the C-terminus. This paper explores the evolution of