Seventy-five women with anti-hepatitis C virus (HCV) antibody were enrolled prospectively during pregnancy or at delivery for study of motherto-child transmission of HCV. Twenty-three women were coinfected with the human immunodeficiency virus (HIV). Seventy babies were monitored for at least 6 mont
Molecular evolution of HCV genotype 2c persistent infection following mother-to-infant transmission
✍ Scribed by M. Rapicetta; C. Argentini; E. Spada; S. Dettori; M. P. Riccardi; M. Toti
- Publisher
- Springer Vienna
- Year
- 2000
- Tongue
- English
- Weight
- 170 KB
- Volume
- 145
- Category
- Article
- ISSN
- 1432-8798
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## Abstract To demonstrate vertical transmission of hepatitis C virus from an HCV infected woman and to assess the evolution of HCV quasispecies in the infant, the variable E2 region was analyzed in one mother‐infant pair at birth and in serial samples from the infected baby. Sequence analysis of t
## Abstract One hundred twenty‐six mother‐infant couples were studied and 105 exposed babies were monitored for at least 12 months to define the risk of mother‐to‐infant HCV transmission. Infection occurred in 5 out of 76 infants (6.6%) born to 69 viraemic mothers and in none of 29 born to 26 non‐v