✦ LIBER ✦

Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function

✍ Scribed by Graham RL Cousins; Sally-Ann Poulsen; Jeremy KM Sanders

Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 458 KB
Volume: 4
Category: Article
ISSN: 1367-5931
DOI: 10.1016/s1367-5931(00)00088-0

No coin nor oath required. For personal study only.

✦ Synopsis

The principles of Darwinian evolution have been explored in molecular systems such as autocatalytic networks and dynamic combinatorial libraries. Molecular evolution in such systems manifests itself as ligand or receptor amplification by selection. Research efforts exploring these concepts may provide a mechanism for the identification of novel catalysts, molecular receptors and bioactive molecules.

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