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Molecular epidemiology of two consecutive outbreaks of adenovirus 8 keratoconjunctivitis

✍ Scribed by Professor C. Chastel; T. Adrian; M. Demazure; M. C. Legrand-Quillien; B. Lejeune; J. Colin; R. Wigand

Book ID
102377908
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
384 KB
Volume
24
Category
Article
ISSN
0146-6615

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✦ Synopsis

Eleven strains of adenovirus 8 (Ad 8) isolated during two consecutive outbreaks of epidemic keratmnjunctivitis (EKC) in the Ophthalmology Department of a University Hospital in France were cumpared by DNA restriction anaIysis. The results indicated that isolates from the two outbreaks belong to the same genome type, which is also the most predominant genome type of Ad 8. The usefulness of molecular epidemiology in Ad 8 infections is briefly discussed.

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✍ Jan C. de Jong; Marc DΓ©mazure; Marie-Christine Legrand-Quillien; GeneviΓ¨ve Le La πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 576 KB

## Abstract Four consecutive epidemics of keratoconjunctivitis caused by adenovirus 8 (Ad81 occurred over a 5‐year period in Brest, France. A selection of 30 strains isolated during this period was studied by DNA restriction enzyme analysis using nine restriction enzymes. Bgll and Sac1 were the mos