## Abstract Respiratory syncytial virus (RSV) causes significant burden of disease during infancy and childhood. This study examined the genetic relatedness of RSV positive samples from child inpatients and outpatients and a birth cohort from a rural coastal district of Kenya and also the distribut
Molecular epidemiology of respiratory syncytial virus
β Scribed by Patricia A. Cane
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 179 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1052-9276
- DOI
- 10.1002/rmv.305
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β¦ Synopsis
Abstract
Human respiratory syncytial virus (RSV) is the major cause of lower respiratory tract disease in infants. It is unusual in that it causes repeated infections throughout life. Despite considerable efforts there is as yet no satisfactory vaccine available. This paper reviews the molecular epidemiology of the RSV and describes the complex genotypic structure of RSV epidemics. The evolution of the virus is discussed, with particular reference to the antigenic and genetic variability of the attachment glycoprotein. Copyright Β© 2001 John Wiley & Sons, Ltd.
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