✦ LIBER ✦

Molecular epidemiology of hepatitis C virus infection amongst intravenous drug users in rural communities

✍ Scribed by Ayaz Majid; Roger Holmes; Ulrich Desselberger; Peter Simmonds; Tom A. McKee

Publisher: John Wiley and Sons
Year: 1995
Tongue: English
Weight: 483 KB
Volume: 46
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890460111

No coin nor oath required. For personal study only.

✦ Synopsis

The prevalence of hepatitis C virus (HCV) infection amongst a group of intravenous drug users (IVDUs) resident in West Suffolk (East Anglia, England) was investigated and compared with the prevalence of infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV). In addition, both the level of HCV persistence, as defined by detection of viral RNA, and the HCV genotypes present in this population were determined. It was found that HCV antibodies were present in 59% of those tested; by comparison 22% had antibodies to HBV and 1% antibodies to HIV. HCV RNA was found in 44% of those with HCV antibody. HCV genotype 1 was the most prevalent within this population although both genotypes 2 and 3 were also represented.

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