Molecular epidemiology of dengue virus type 3 in Northern South America: 2000–2005

✍ Scribed by Tadeusz Kochel; Patricia Aguilar; Vidal Felices; Guillermo Comach; Cristopher Cruz; Aracely Alava; Jorge Vargas; James Olson; Patrick Blair

• Book ID: 104053213
• Publisher: Elsevier Science
• Year: 2008
• Tongue: English
• Weight: 638 KB
• Volume: 8
• Category: Article
• ISSN: 1567-1348
• DOI: 10.1016/j.meegid.2008.06.008

✦ Synopsis

A phylogenetic approach was used to identify genetic variants of DENV-3 subtype III that may have emerged during or after its expansion throughout South America. We sequenced the capsid, premembrane/membrane and envelope genes from 22 DENV-3 strains isolated from Venezuela, Bolivia, Ecuador and Peru between 2000 and 2005. Phylogenetic analysis showed that the isolates sequenced in this study formed three clades within subtype III: one with the isolates from Venezuela, one with the Bolivian isolates and one with the isolates from Ecuador and Peru.