## Abstract Twentyโtwo children receiving therapy for leukaemia were studied longitudinally for 23 months for cytomegalovirus (CMV) complement fixing (CF) antibodies and excretion. The frequency of CMV antibodies in these children was similar to that of normal children of the same age. During the p
Molecular epidemiology of cytomegalovirus infection in kindergarten children
โ Scribed by Shen, Chen-Yang; Chang, Bao-Li; Chang, Shu-Fen; Yang, Show-Lin; Tseng, Su-Ling; Chen, Chi-Yu; Wu, Cheng-Wen
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 601 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
โฆ Synopsis
This study was conducted to determine the source of cytomegalovirus (CMV) excretion in children who had persistent viruria. A total of 287 children, ages 3-5 years, enrolled in two kindergartens were followed for 9 months, and 28.8% of 139 CMV-infected children were found to have shed virus persistently in urine for 23 months. A polymerase chain reaction (PCR)-based method provided direct evidence to demonstrate differences in CMV strains shed by 32 persistent shedders selected at random. The glycoprotein B (gB) nucleotide regions of CMV were amplified and analyzed by restriction enzyme digestion. The CMV strains shed by most of these children showed different restriction profiles compared with strains from their playmates. It is considered that persistent reactivation of endogenous CMV is the most plausible explanation.
๐ SIMILAR VOLUMES
## Abstract The source of human cytomegalovirus (HCMV) infection was investigated in 29 pregnant women with primary HCMV infection by comparing DNA sequences of UL146, UL144 and a portion of UL55 gene of HCMV strains circulating within each family. Thirteen families were identified in which the pre
## Abstract The national reference laboratory for calicivirus diagnostics monitors the epidemiology of calicivirus infections in Norway. During winter 1998โ1999, 406 fecal samples were received from patients with suspected calicivirus infection. Of these, 76 (19%) were calicivirus positive by a nes
## Abstract Rotaviruses and noroviruses are leading viral causes of diarrhoea in children. A crossโsectional study was undertaken among children aged <5 years with acute gastroenteritis at AlโJala Children's Hospital, Tripoli, Libya, from October 2007 to September 2008. Of 1,090 fecal samples colle
## Abstract The genetic diversity of the hepatitis C virus (HCV) in Cyprus is investigated for the first time in this study. Nucleotide sequence analysis of the COREโE1 and NS5B regions of the HCV genome was performed on blood plasma samples obtained from 77 HCV patients in Cyprus, collected during
## Abstract Thirtyโnine children without previous cytomegalovirus (CMV) infection received blood transfusion in the National Taiwan University Hospital. The overall transfusionโacquired CMV infection rate was 36% (14/39). Donor CMV seropositive rate was 70%. None of the nine children who had receiv