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Molecular epidemiological studies of human herpesvirus 6 in families

✍ Scribed by Tetsu Mukai; Takeshi Yamamoto; Toshio Kondo; Kazuhiro Kondo; Toshiomi Okuno; Haruhiko Kosuge; Dr. Koichi Yamanishi

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
454 KB
Volume
42
Category
Article
ISSN
0146-6615

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✦ Synopsis

Abstract

The mode of transmission of human herpesvirus 6 (HHV‐6) was investigated by molecular epidemiological techniques in four families. HHV‐6 was isolated from the peripheral blood of seven infants with exanthem subitum, including siblings, and from the saliva of two mothers. These isolates were examined for genetic relatedness by means of restriction enzymes analysis of purified DNA. While the profiles of the digestion patterns differed among families, they were very similar in a particular family. These results may suggest that HHV‐6 is transmitted primarily from mother to child. © 1994 Wiley‐Liss, Inc.

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