Molecular dynamics studies of a phospholipid bilayer and its analysis using focus
β Scribed by A.P. Lemon; D.J. Osguthorpe; M.M. Campbell
- Book ID
- 103638117
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 160 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0263-7855
No coin nor oath required. For personal study only.
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## Abstract The hERG potassium channel has recently been a matter of extensive studies both at experimental and computational levels, because of its possible involvement in the potentially lethal drugβinduced long QT syndrome. In this context, in the absence of an experimentally determined 3D struc
Gossypol (1,1 ',6,6 ',7,7'-hexahydroxy-5,5 ' -diisopropyl-3,3 '-dimethyl[2,2'-binaphthalene]-8,8' dicarboxaldehyde) previously used as a male oral contraceptive is an amphiphilic compound. At low concentrations, it is expected that gossypol would intercalate into the phospholipid bilayers. To demons